The story begins in 2011 and follows Josuke Higashikata, a young man afflicted by retrograde amnesia, in his search to uncover his identity in Morioh Town, a coastal Japanese town affected by the Tohoku earthquake. However, his digging pulls him and his adoptive family into the unfinished business between his previous life and an impending inhuman threat.
JoJolion represents the second part of the series set in the Steel Ball Run Universe.
An Amnesiac Man
Yasuho Hirose, hiding from Joshu Higashikata near Morioh Town's Wall Eyes, discovers a man in a sailor cap half buried underground. After she calls an ambulance, Yasuho notices a star-shaped birthmark on his shoulder surrounded by a fresh bite mark. Moreover, the man asks for his name. After she pulls him out of the ground, she notices the man to be completely naked, and that is when Yasuho discovers he has four testicles. Then a fight erupts between Joshu and the amnesiac, during which a soap bubble emerges from the sailor's shoulder and seemingly makes Joshu's eyes pop. The man faints, before they are all taken to hospital.
In narration, Yasuho explains how the Wall Eyes rose concurrent with a version of the 2011 Tohoku earthquake. Massive, rocky protrusions marked with long, vertical holes, they rise between the coastline and the mainland, blocking highways, waterways, gas and power lines.
The First Clue
Later at the hospital, Yasuho meets the young man again and he explains to her that he is amnesiac. Yasuho offers to help him and by investigating his hat, they manage to seemingly learn his identity: Yoshikage Kira. However, Yasuho feels this name doesn't fit him and instead nicknames him "Josuke". The duo goes to Kira's apartment, where Josuke discovers a naked woman in the bathtub. Yasuho and Josuke try to ask the woman who she is, but she doesn't answer. Yasuho discovers a compromising photo album containing pictures of the woman having erotic bondage with what appeared to be Josuke. Convinced that Josuke is a sadist, Yasuho leaves in despair. Moreover, Josuke notices that he is under attack: each time he injures his hand or foot, it falls under the control of an aggressor in the flat above him. Revealing his Stand Soft & Wet and with Yasuho's timely return, Josuke manages to catch his opponent.
The attacker presents himself as Ojiro Sasame, a surfer seeking revenge against Yoshikage Kira and who confirms that Josuke isn't Kira although he bears a passing resemblance. Sasame tells of a psychopathic Kira, who in the past by an obscure power and for little reason convinced Sasame to eat his own fingers. Josuke sees a photo of Kira near the Wall Eyes and comes back to where he emerged to uncover the body of the real Yoshikage Kira, who died of cardiac arrest three days prior. Yasuho secretly obtains the autopsy results and discovers something else: Kira's corpse is missing both of his testicles.
The Trail of the Higashikatas
- Main article: JJL Chapter 11, Family Tree
- Main article: "Paisley Park" and "Born This Way" (story arc)
- Main article: JJL Chapter 17, The Lemon and the Tangerine
Yasuho introduces Josuke to the head of the Higahikata family, Norisuke Higashikata IV, owner of a fruit importation business inherited from his grandfather Norisuke Higashikata I. Lent the Higashikata name, Josuke Higashikata is welcomed into Norisuke's home and is instructed to guard the youngest daughter Daiya. As Norisuke ominously warns him to obey his word, Yasuho is escorted out by the family's maid Nijimura and warned not to return.
As everyone leaves, Daiya begins to flirt with Josuke and decides to play with him. Using her Stand California King Bed, she steals one of Josuke's few memories every time he fusses over her. To make things fair, she tells Josuke that if he manages to make her step on his shadow, the memories will be returned to him, although her knowledge and perceptiveness make the endeavour nearly impossible for him. Meanwhile, Yasuho discovers from a DNA test that Josuke and Kira are practically the same person. Josuke eventually tricks Daiya into stepping on his shadow cast from the light of an open refrigerator. Josuke decides to not hold a grudge and enters Norisuke's study, following the symbol he's seen on Kira's wrist.
Josuke discovers a book in the study marked with the same symbol: a record of the Steel Ball Run race. In the front cover he discovers a family tree for the Higashikata family, and that the first Norisuke Higashikata's daughter married Johnny Joestar, a direct ancestor of the dead Yoshikage Kira. From the family tree, Josuke makes plans to seek out Kira's only living relative: his mother Holy Joestar-Kira. With Yasuho's help, Josuke discovers that she is a doctor at local T.G. University Hospital and both agree to meet here. Also, they discover that she is currently a patient. On his way to the hospital, Josuke notices that his GPS is malfunctioning and that a motorcyclist Stand is stalking him, appearing suddenly and attacking with a freezing wind before disappearing just as quickly.
The GPS is eventually revealed as Yasuho's own nascent Stand, which is actually helping Josuke against his assailant. Noticing that the enemy can only appear when he "opens something", Josuke manages to evade his assailant, then find and eventually defeat the user Kyo Nijimura. Kyo is revealed to have a star-shaped birthmark and to be Kira's little sister. She mistook Josuke for an enemy and tried to stop him from approaching her mother Holy; as a gesture of good will, Josuke promises to stay away from Holy and the two make peace.
Privy to the supernatural properties of the soil near the Wall Eyes, Kyo and Josuke work out that Josuke is a mix between two men, demonstrating the process with two fruits. However, Kira's Stand was not Soft & Wet but rather Killer Queen, leaving the identity of the other man a mystery.
Meanwhile, Yasuho has managed to enter the hospital and meet the delirious Holy Joestar-Kira, but she is soon kicked out by security. Holy watches on as she sees Yasuho's Stand Paisley Park, activate subconsciously, musing that she may be able to help her son. Paisley Park's powers ultimately lead Yasuho back into the hospital into a room right next to Holy's where she sees the extent of her mysterious illness. She lacks the ability to discern people from objects, and the doctors note that she is missing several of her vital organs and her brain has perfectly spherical voids in it, but there is no sign of surgical removal.
Shakedown Road & Johnny Joestar
Several days later, Norisuke asks Joshu to take Josuke down to the local high school to see if he can be enrolled there. However, the path to the high school leads them through Shakedown Road, where the residents of the road somehow make Joshu and Josuke damage miscellaneous items and coerce them into compensating with increasingly more money. As a pet shop owner demands 330,000 yen in compensation for a killed rare turtle, Joshu and Josuke reluctantly become mules for a drug trade as pair of cops watch on.
Josuke and Joshu separately understand how Shakedown Road works and exploit it to their advantage. Seemingly taking the money and fending off the thug with his newly awakened Stand Nut King Call, Joshu sees that he's been tricked. In truth, Josuke had performed another exchange and clears his name with the policemen, also acquiring the money for the trade to reimburse to old man. Afterward, Yasuho and Josuke respectively learn through research and the revelation of the pet shop owner that a nearby Jizo was built as a memorial to Johnny Joestar and discover the circumstances of his death.
After the Steel Ball Run Johnny had married Rina Higashikata whom he met on his way to Europe. After a few years of happy life, Rina was struck by a mysterious disease: she began to lose her memories and her skin turned to stone. In his anguish, Johnny stole the Saint's Corpse and took it to Japan. Hiding the Corpse in a hole under a pine tree, Johnny brought his family here and prayed the Corpse to transfer the disease away from his wife, Johnny saw with horror that his son became ill instead. Finally, Johnny took the disease onto himself and died, his head crushed by a rock.
The pet shop owner claims that his story is a mere legend, but Josuke realizes the link between the mysterious illness that afflicted Rina and the one Holy Joestar suffers from to this day.
Elsewhere, Yasuho finds her way to the Meditation Pine at the rear of the Higashikata estate from photos in the news stories she has researched. She reads of a baby who washed up on the beach nearby on November 13, 1901, wearing a necklace. Yasuho is suddenly grabbed by a hand from inside the tree and momentarily groped in the darkness.
A New Enemy: The Rock Humans
- Main article: Paper Moon Deception (story arc)
- Main article: JJL Chapter 26, Tsurugi's Goal & the Architect
- Main article: JJL Chapter 30, King Nothing
- Main article: "I Am a Rock" (story arc)
Yasuho finds herself with Tsurugi Higashikata, the grandchild of Norisuke. Tsurugi reveals that they are in an underground facility used by the Higashikata Family. Tsurugi and Yasuho chat, and Tsurugi reveals that he's a boy crossdressing to thwart off a family curse. When Yasuho demands that he allows her to leave, Tsurugi pulls a prank on her. He has folded Yasuho's smartphone into a frog which leaps at her and she is suddenly put under the thrall of Paper Moon King.
Yasuho leaves and heads back into town, followed by Tsurugi, and discovers that she cannot distinguish between people anymore. Although she calls Josuke for help, Tsurugi neutralizes him with his power as well. After a lengthy series of misadventures, Yasuho relents and follows Tsurugi back to the playroom. Elsewhere, Josuke sees that he is no longer afflicted by Tsurugi's Stand and realizes that Yasuho was its main target.
Through the slot in the door of the second underground room, somebody spies on Tsurugi and Yasuho's return.
Battle Against Yotsuyu Yagiyama
Tsurugi apologizes, admitting that he targeted her with his Stand Paper Moon King. Calmed, Yasuho asks Tsurugi the purpose the underground complex and she learns that it is dedicated to treating the mysterious illness that affects the first born members of the Higashikata family which slowly turns their skin to stone. Yasuho is reminded of Holy's condition and that Kira tried to save his mother. After Tsurugi leaves, a mysterious man named Yotsuyu Yagiyama appears and attacks Yasuho.
Meanwhile, Josuke spots Tsurugi heading toward the garden and follows him, himself followed by Norisuke. Josuke then interrogates Norisuke to discover his intentions once and for all. Despite earlier suspicious behavior, Norisuke exposes why he doesn't mean Josuke any harm and that both him and Kira wanted to cure the Rock Disease plaguing their families. Norisuke thus hoped to learn in Josuke's memories the cure Kira supposedly found before his death.
Soon the two men are attacked by miscellaneous objects that keep converging into Josuke after Yotsuyu somehow sneaks on Josuke and touches him. Josuke and Norisuke take refuge in the bunker where they learn that Yotsuyu has promised Tsurugi to give him a cure in exchange for giving Josuke away. When Josuke sees that Yasuho has been taken, he immediately gives chase with Norisuke's Stand King Nothing which tracks objects and people by their scents. While following the scent, Norisuke reveals to Josuke the Rock Disease which affects the eldest child of each generation and how and member sacrifices themselves for the child's sake. King Nothing leads Josuke and Norisuke to the coast in which they find Yasuho still unconscious. At the same time, they discover Yotsuyu and see that he somehow can turn into a rock. Yotsuyu attacks again with canisters of pesticides but Josuke grabs him and jumps off a cliff into the sea below. He then traps him in nets and threatens to drown him if he doesn't answers his question, but Yotsuyu remains silent before crumbling to dust. At the same time, Josuke spots a mysterious fruit amongst the flotsam but it soon sinks deep into the water.
Josuke returns to the surface with what remains of Yotsuyu, only raising more questions than answers when examining the net full of stones. Tsurugi asks if he saw the cure Yotsuyu had promised him, and Josuke mentions the fruit.
The Trail of the Fruit
- Main article: JJL Chapter 33, Josuke! Go to the Higashikata Fruit Parlor
- Main article: Every Day Is a Summer Vacation (story arc)
- Main article: JJL Chapter 38, Jobin Higashikata Is a Stand User
- Main article: Doobie Wah (story arc)
Jobin Higashikata's Involvement
After some research, Norisuke reveals that Yotsuyu was impersonating someone and in reality has no identity. Meanwhile, Yasuho has been sent home. Norisuke, Josuke, and Tsurugi soon find another fruit alongside a dog which can transform into rock, and Norisuke makes King Nothing memorize its scent. Tsurugi adopts the dog which he dubs Iwasuke.
To investigate the fruit further, Norisuke brings Josuke to his fruit parlor to examine an encyclopedia, but they are interrupted by the return of Norisuke's first born son Jobin Higashikata. Jobin has just returned from a trip abroad and gives Josuke a rare Dorcus Titanus Palawanicus stag beetle. Overjoyed to see his eldest son, Norisuke decides to accompany him back home, and unbeknownst to him, King Nothing detects the mysterious fruit's scent on Jobin's handkerchief, a fact only Josuke notices.
Josuke enlists Tsurugi's help and learns that he can bait Jobin through his prized beetles. Thus Josuke manipulates Jobin into starting a beetle fight with Joshu as an observer. Josuke plants female beetle pheromones on the ring and manages to win the first bout, but Jobin asks for a second bout with his car as a prize, which was Josuke's goal. During the second bout, Jobin then cheats too, unveiling a small part of his Speed King's heat power to get the upper hand in the beetle fight but Josuke sneakily poisons Jobin's beetle and wins the car keys.
During the challenge, Tsurugi has also enlisted Yasuho and made her enter the Higashikata House. After Josuke sends them the car keys with a bubble, Yasuho and Tsurugi enter the garage and investigate where Jobin has gone with his car thanks to Paisley Park. That way, they see that Jobin has given the tree for the mysterious fruit to an unknown man. Meanwhile, Jobin has begun to suspect Josuke and tries to pressure him into revealing his intention with Speed King; however, Josuke escapes. So do Yasuho and Tsurugi.
Battle Against Aisho Dainenjiyama
Yasuho discovers the man's identity as Aisho Dainenjiyama, a security guard at Morioh's baseball stadium. Using Yasuho's phone empowered by Paisley Park and folded up by Paper Moon King into a frog, the duo witness Aisho perform a fruit deal with an old man who miraculously regrows a lost leg. However, Aisho discovers the phone. Although the phone escapes, Aisho unleashes his Stand Doobie Wah! to chase Yasuho and Tsurugi. The automatic Doobie Wah! materializes from their own breath and relentlessly pursues them.
A flashback details Aisho's past: he used to live in a house with a girlfriend, but when he revealed his true nature as a rock man, his girlfriend used one of his hibernation periods to sell the house, nearly killing him in the process when it was demolished; Aisho was saved when Yotsuyu woke him up and lamented at the loss of his house.
In the present, Tsurugi retaliates by releasing a car origami that makes contact with Aisho and tricks him into mistaking a bus for Jobin, causing Aisho to be run over and die.
An Old Acquaintance
- Main article: Love Love Deluxe (story arc)
The next day, Yasuho finally meets up with Josuke, again. They stroll along the beach, sharing a tender moment, but another girl suddenly greets Josuke as "Se-chan", asking for a later meeting. Josuke goes to meet the girl, named Karera Sakunami. Despite her suspicious behavior, Karera is familiar with the person Josuke was, and he plays along, hiding his lost memories and Karera does reveal his name: Josefumi Kujo. Meanwhile, a pair of twins playing football, the A. Phex Brothers, track Karera and attack her.
The nature of Rock Humans is explained, revealing their coexistence with humanity in secret, the prevalence of Stands amongst them, and the seeming cursed interactions they have if they fall in love with a human.
A short fight ensues between Josuke and the A. Phex Brothers. Josuke manages to use Schott Key No.2's poison gas to his advantage and takes the elder brother hostage with bubbles full of poison. When the elder, soaked with gasoline, is ignited by Karera, his brother runs toward him, forgetting the bubbles which pop and envelop him in poison gas. Both Rock Men are consequently killed. After watching the fight, Karera finally realizes that Kira and Josuke had performed an equivalent exchange, and leaves Josuke be before he can ask her anything else.
Battle Against Tamaki Damo
- Main article: Hato Brought Her Boyfriend Home (story arc)
- Main article: Vitamin C and Killer Queen (story arc)
- Main article: JJL Chapter 54, Walking Heart
- Main article: JJL Chapter 55, Breaking Heart
The mysterious Locacaca Tree is introduced, being a plant from New Guinea formally discovered by an Australian expedition in 1938. The Locacaca was used by the locals to cure various ailments while turning a random body part into stone. During World War II, all reports of the fruit disappeared and it became a mere legend.
As Josuke rests in the Higashikata House and converses with Yasuho, Hato brings her new boyfriend Tamaki Damo to meet her family. Surprisingly, Damo is unattractive and awkward, leading to an embarrassing meeting. However, the whole family is soon immobilized by Damo's Vitamin C which softens them into puddles. Damo confronts Norisuke and interrogates him in order to find who has been dismantling his organization. Damo then explains the context of the whole affair.
Two years ago, Yoshikage Kira discovered Aisho Dainenjiyama in his rock form by accident while working on a ship. Curious, he investigated the whole trade and discovered the Locacaca. He coincidentally met with an acquaintance, Josefumi. Back when he was a boy, Josefumi was saved by Holy Joestar-Kira and Yoshikage, who performed surgery on him. Grateful, Josefumi agreed to help Kira steal some branches from Aisho unnoticed and subsequently grafted the branches to another tree. However, in August 19, 2011, Josefumi and Kira were caught by Damo and Yotsuyu. Kira was fatally wounded but he snuck some of Killer Queen's bomb near them, causing an explosion. This allowed Josefumi to drag Kira to the hiding spot of the two fruits they had. Although he drove off the A. Phex Brothers, Josefumi wasted the fruits trying to save Kira but noting their new ability to fuse, decided to fuse himself to Kira in the hopes of Kira surviving and harvesting new fruits. A rift opened and the two men were buried underground.
Back in the present, Hato confronts Damo over what he is doing but Damo takes her out to confront Josuke after Norisuke reveals Josuke's identity. Damo almost kills him but is interrupted as Josuke has transported Hato out of the house. Thanks to her Walking Heart, Hato inflicts severe damage and Josuke can finish Damo off. He subsequently confirms that he is the amalgamation of Yoshikage Kira and Josefumi Kujo.
Meanwhile, Norisuke's wife Kaato Higashikata has finished her prison sentence and prepares to leave. She notably contacts her son Jobin in order to plot against Norisuke.
Interlude & Aftermath
- Main article: Milagro Man (story arc)
- Main article: JJL Chapter 58, Dawn of the Higashikata Household
Two weeks prior to Kaato Higashikata's release, Joshu asks his father for some money to buy some idol goods. After the idol meet-and-greet, Joshu antagonizes a fellow fan and secretly steals his wallet after he leaves it behind at the register. Joshu indulges himself in a shopping spree, and coincidentally accumulates more and more money as he tries to spend it. People actually refuse to take money from him, mentioning a mysterious Milagro Man. Discovering that the money is literally clinging to him and is burdening him more and more Joshu tracks down his victim Zaihei Nigatake. Zaihei, grateful toward Joshu for taking his "curse", explains the legend of the Milagro Man and his history with the curse. Nonetheless, Joshu tricks Zaihei into tearing one of the cursed bills and passes the curse back onto him much to Zaihei's horror. On his way home, Joshu melancholically ponders his true worth in the world.
Josuke confirms his second identity, then finally sees Holy Joestar-Kira for the first time. However, her condition has deteriorated drastically and Josuke is appalled that the hospital staff don't take care of her. Feeling attachment toward her, he swears to find the cure and pay for Holy's treatment in the meantime.
Afterward, the Higashikata family notices that their mother Kaato has returned home. Norisuke and Hato are wary of her because they know she was sent to prison for murdering a child. The meeting is ruined because of Joshu and Kaato storms out of the house, still determined to have her due for protecting the family.
The New Locacaca
Seeking the Plant Appraiser
- Main article: Dolomite's Blue Lagoon (story arc)
- Main article: The Plant Appraiser - Rai Mamezuku (31) (story arc)
- Main article: Urban Guerrilla and Doremifasolati Do (story arc)
Sometime later, Josuke reveals Holy's condition to Norisuke and also that Jobin may be somehow conspiring against all of them due to his involvement in the Locacaca Smuggling Organization. Norisuke refuses to suspect Jobin but instructs Josuke to seek out his company's plant appraiser to find the branches. Kaato eavesdrops on this conversation and informs Jobin of the two's plans. Jobin in turn seeks out another Rock Human named Dolomite who agrees to attack Josuke under the belief that he will get his body back to normal, summoning up his Stand Blue Hawaii. Blue Hawaii then controls several consecutive people to try and touch Josuke so that he is controlled. Despite his best efforts, Josuke is touched by a baby. The controlled Josuke heads to the Mutsukabe Shrine, where he is interrogated by Dolomite about his goals. Once he discovers the truth, Dolomite instructs Josuke to drown himself in the pond, but Yasuho thankfully intervenes.
After Dolomite is neutralized and reveals Jobin's involvement with the Locacaca Organization, Josuke and Yasuho go to the plant appraiser's home on a bus. Suddenly, Rai Mamezuku the plan appraiser appears to hijack the bus. He notably tells Josuke that a new group of enemy is now moving against them and Mamezuku brings the couple to his home: a ski lift. He also reveals Doggy Style, a Stand ability allowing him to unravel himself. The trio is soon attacked by a duo of new enemies: Urban Guerrilla and Doremifasolati Do. Urban is a Rock Human and Doremifasolati is his pet which functions as an underground carrier. Because of their strong abilities, the two almost kill Josuke, Mamezuku and Yasuho but they manage to leak some gas inside of Doremifasolati Do and ignite it, creating an explosion that kills them both.
Interlude: Yasuho's Past
- Main article: JJL Chapter 71, The Qing Dynasty Hair Clip
After the battle, Mamezuku tells Yasuho to go home and stay safe. However, the clash with the Rock Humans causes her to remember an incident of the past. When she was 13, Yasuho bought a hair clip in anticipation of a weekend with her father. However, the hair clip was a strange creature that tricked her into committing suicide. Thankfully, the Kira Family saved her from it. Since then Yasuho keeps its remains in her room.
In the present, Yasuho reaffirms her will to help in front of Mamezuku, who notes that the hair clip may be a Rock Animal and thus a lead toward identifying the enemy.
The Theft of the Locacaca Branch
- Main article: JJL Chapter 72, North of the Higashikata Estate. The Orchard
- Main article: Poor Tom and Ozon Baby (story arc)
It is breakfast at the Higashikata. Jobin stealthily plants Ozon Baby in the orchard, but when he returns to the tool shed, is confronted by his son Tsurugi. Jobin thus reassures that his actions are for the sake of his family.
Nonetheless, the air pressure increases and the Stand Ozon Baby appears to attack everyone.
The Higashikata House is under attack from Ozon Baby which manipulates pressure, everyone save Jobin having fallen unconscious. Trapped in their shed, Jobin and the revived Tsurugi realize that Ozon Baby is an automatic Stand which will indiscriminately attack anyone in its range. Jobin also roughly grasps the enemy's ability: Ozon Baby can decrease the air pressure in a zone, but any closed space will dampen its effects. Determined, they set the orchard on fire by using origamis and Speed King to spur their enemies into action.
Indeed, Poor Tom rushes into the orchard to retrieve the branch while Josuke and Mamezuku go out, protected by Soft & Wet's bubbles. They meet just as Mamezuku takes the branch and a fight ensues. Poor Tom takes out Mamezuku and seize the branch but is poisoned by a yew seed. Pursued by Josuke, Poor Tom is bluffed into cancelling the air pressure ability, but his supposed allies from the hospital have arrived. Surprisingly, Poor Tom is killed by a mysterious ability shooting through his head. An unseen person seizes the branch and drives away before Josuke can do anything. However, it is revealed that Tsurugi used Paper Moon King to trick everyone: an ordinary branch has been fought over while Jobin stole the real Locacaca branch. They hide the branch, grafted into a cactus. Meanwhile, the ambulance driver discover the trick and guess that the arsonist is the one who has the branch.
Finally, Josuke returns to Mamezuku, revealed to be alive and slowly reconstituting himself. Desperate, Josuke can only observe his total loss.
The TG University Hospital
- Main article: Doctor Wu and Awaking 3 Leaves (story arc)
- Main article: Countdown to the Harvest
- Main article: The Head Doctor of TG University Hospital (story arc)
After the fire, the whole Higashikata Family gathers, allowing Josuke to explain his situation and that he has now 10 days to retrieve the fruit. Jobin's insistence on the hospital clues Mamezuku in as to the eldest son's guilt about the fire but the two decide to search the TG University Hospital first for the occupants of the ambulance.
For her part, Yasuho has already headed to the hospital. Yasuho sees Mitsuba Higashikata with a physician, Dr. Wu Tomoki and discovers that he too is dealing the Locacaca to Mitsuba as a form of "beauty treatment". Tomoki, who can turn into dust thanks to his ability Doctor Wu attacks Yasuho but Mitsuba intervenes with her Stand Awaking III Leaves, realizing she doesn't remember how she is treated and determined to save her unborn baby from the equivalent exchange. Fending off Tomoki until they discover a hidden laboratory and a garden of orchard of Locacaca, the two women are almost killed by Tomoki but then saved at the last moment by Josuke who kills Tomoki.
Chasing after the Locacaca
- Main article: The Wonder of You (The Miracle of Your Love) (story arc)
Josuke, Yasuho and Mamezuku check the entry log of the laboratory and discover the supposed remaining member of the Locacaca Organization: Satoru Akefu the head doctor of TG University Hospital. Against Yasuho's instinct they persist in this lead. Unable to find a picture of the doctor, the group tries to chase after him but an unknown Stand prevents them from reaching Akefu, who eventually escapes. Moreover, the group has been crossing path with Tooru, Yasuho's ex-boyfriend. Tooru tries to revive the flame between him and Yasuho, causing no small amount of jealousy and suspicion. Josuke is made to look like a murder culprit when a man's neck snaps after getting into a fight with him and Yasuho finds herself alone as Mamezuku and Josuke must now deal with the repercussion of the man's death.
Seven days before the harvest, Tsurugi and Mitsuba is accused of having shut iron doors on one of his schoolmates, angering Mitsuba who vehemently defends Tsurugi and insults one of the mothers, Makorin - all the while knowing that Tsurugi had a perfect motive. However, she also sees the head doctor has been near the school gates and when she returns to her home, she spots Akefu again.
Five days before the harvest, Ojiro Sasame learns about the healing soils around the Higashikata House from his current girlfriend Makorin and also remembers the healing properties of the Locacaca. He stalks Tsurugi Higashikata and tricks the boy into going back to the house and inform his father about him. Jobin Higashikata hastily checks on his plant, but realizes that Ojiro has tricked them into revealing their hiding spot. Using Fun Fun Fun, Ojiro controls Jobin into slamming the shards of a broken window into his and Tsurugi's neck and Jobin takes the fruit. He snatches some money from Jobin's wallet but also realizes that he's been tricked. Tsurugi used Paper Moon King to make Ojiro believe the shards were bigger than they really were and Jobin has stored heat into the money, killing Ojiro. Jobin then retrieves the plant and kills Mako Kitani for good measure.
Back at the Higashikata's, Norisuke suddenly reads on the newspapers that Josuke and Mamezuku are suspected of murder and becomes worried. It is revealed that the duo has been hiding for some time. When Mamezuku discovers that Satoru Akefu may be attending a lecture on regenerative medicine at the TG University Hospital, they decide to resume their pursuit but the incoming rain then turns into a deadly hail because of Akefu's ability. Cornered by the police and the rain, Josuke shockingly steps into the rain, determined to be wounded and brought to the hospital. A shocked Mamezuku is left behind, apprehended by the police. Meanwhile, Tooru tries to woo Yasuho but she then discovers that Satoru and Mitsuba Higashikata are acquainted. Learning about the link between Mitsuba Higashikata and Satoru Akefu, Yasuho and Tooru decide to go to the Higashikata House. There is 48 hours left before the harvest.
At the Higashikata's, Mitsuba's suspicions about the events grow as she learns about the repercussions of the struggle for the new Locacaca. Still in the dark and under attack from Satoru's ability, Mitsuba starts to suspect that something is amiss, at which point Tsurugi's Rock Disease goes out of control and his body begins transforming into an origami.
Two days later, Josuke wakes up at the hospital. The lecture is about to begin but his mission is compromised when a policeman he takes out falls onto his body, causing heavy damage. Josuke finds himself in a desperate situation but is thankfully saved by Holy who had woken up, having sensed his arrival. As she drags him toward the gynecology department, room A2 where she was receiving the Locacaca treatment, Holy explains that her condition has worsened and that a mass of rock moving through her body threatens to put her into a coma regularly. Moreover, she explains that the Locacaca Research Organization had infiltrated the hospital long ago, performing clinical trials through Tamaki Damo's smuggling ring. At the same time, Satoru begins his lecture and unveils his new miracle medicine, the Locacaca 6251. Josuke and Holy reach room A2 where Holy is able to heal Josuke with 6251 before losing consciousness. Seeing his mother in this disastrous state, Josuke recovers and is more determined than ever to get his hands on the fruit. Josuke decides to revise his plans and instead of pursuing the head doctor head-on, has an unknown parcel delivered somewhere else and then patiently waits inside the hidden laboratory.
Meanwhile, Yasuho has arrived at the Higashikata House and begins to infiltrate the household to find the new Locacaca. Jumping between electronic devices, Yasuho eventually finds a bedridden Tsurugi and tries to ask him the location of the branch. However, she is interrupted when Jobin grabs the mobile phone Paisley Park is hiding in and throws it in the toilet in an attempt to drown Yasuho. Worse, the phone's signal is breaking off. Isolated from any electronic device and any ally as she cries for help, Yasuho resorts to showing herself to the cameras. Mitsuba spots her and goes to Tsurugi's bedroom. However, Jobin's orders and the sight of Satoru Akefu lurking near makes Mitsuba determined to protect her family at all costs. To keep the cure for her son safe, Mitsuba leaves Yasuho for dead. As Yasuho comes face to face with the head doctor, she falls down and loses her right arm. Mitsuba then tries to finish off Yasuho by summoning Awaking III Leaves and remotely pushing the cell phone deeper into the water, but a drip of water pierces her hand. This causes her to misplace one arrow and the energy is redirected into a wall. The wall is destroyed and reveals to the rest of the family the new nearly matured Locacaca.
- Main article: Endless Calamity (story arc)
Upon arriving at Tsurugi's bedroom, Norisuke sees Paisley Park and immediately saves it from drowning while demanding to know what is happening. Jobin tries to sway Norisuke to his side, but Norisuke summons King Nothing, which investigates the new Locacaca. It materializes into Ojiro Sasame, showing the family that Jobin is connected to his death. Overwhelmed by the pressure, Jobin resorts to inducing a heat stroke in Norisuke with Speed King. He cries at his action but quickly recomposes himself to lead the Higashikata Family. While this is going on, Paisley Park has managed to return to Yasuho in the confusion, all the while Satoru Akefu continues to lurks near the house.
At the police station, Mamezuku manages to work out that the head doctor he sees is the Stand, whose power is fueled by the karma of those who witness it. Meanwhile, Yasuho calls Tooru and asks for his help. He seems interested when she mentions a way to heal her and decides to drive towards the Higashikata House. Back inside the house, Jobin tells his siblings to put the unconscious Norisuke on the second floor and the Locacaca in another hiding spot. Mitsuba then sees the head doctor, who keeps approaching in impossible ways such as going from a corridor to a computer screen, then passing across the bathroom and then under the bedsheets. Mitsuba warns Jobin about the head doctor and, also realizing the nature of the enemy's ability, warns Jobin to not go after him. However, Jobin has summoned Speed King and attacks the doctor under the bedsheets. Nothing grave seemingly appears, but Jobin then realises that the dip tube of a hair spray has been shot into his chest, letting blood flow out of his body at a dramatic rate. Jobin collapses and the potted Locacaca rolls towards the door to the garage. Meanwhile, Yasuho is still agonizing outside and Tooru, who has arrived, merely stands by. Joshu suddenly comes out of the house with the potted Locacaca, intending to help her.
Meanwhile, Josuke's parcel has arrived to its receiptor, a journalist that has assisted to Akefu's lecture. The parcel contains damning evidence of illegal human trials of the Locacaca6251 and the journalist confronts Akefu over this, only to be killed. Akefu heads for the laboratory and Rai incidentally spots him. Rai and Akefu roughly reach Josuke at the same time. Josuke has a plan but Akefu refrains from stepping inside of the room. Instead, he brings out a creature named Dododo De Dadada which attacks Josuke. Thanks to his bubbles preventing from touching anything, Josuke avoids being heavily wounded. Akefu dares Josuke to come at him, but Josuke points out that if Akefu had the new Locacaca, he wouldn't need to. Thus, Rai realizes that Akefu doesn't have the fruit.
Ensue a detailed explanation of the early life of a Rock Human, a more detailed explanation of their habits, and then a flashback. A young Rai just finished attending to his father's funeral and his family orchard has been destroyed by a mysterious calamity. Despite having seen a mysterious insect attacking the trees, Norisuke Higashikata IV, who had come to the funeral and knew the Mamezuku, refutes Rai's claims and say that these events were natural calamities. Incidentally, Rai spotted the head doctor there. In the present, Josuke suddenly oozes asbestos but Rai protects him from Dododo De Dadada's second attack and thankfully tells him not to move. The attack was similar to the way the trees in the orchard died and thus Rai is able to give a good advice. However, Satoru Akefu, or rather the Stand Wonder of U precises that extending one's limbs is the trigger for the asbestos, but also practically reveals to Rai that he was the one responsible for Rai's father's death and the destruction of the orchard. Dododo De Dadada attacks Josuke again.
Josuke is unable to defend himself from Dododo's attack and his attempts to counterattacks are fruitless as he's handicapped by the asbestos gushing out of his body, including the eyes. As Dododo ambushes Josuke and attempts a finishing blow at his throat, Rai unravels himself. Crawling like a snake on the ceiling, Rai takes Dododo De Dadada by surprise and kills it by stabbing it with his fingertip. While Josuke recovers, Rai confronts Wonder of U and his fingertip is mere centimeters from its face. Nonetheless, Wonder of U keeps taunting Rai about his family and pushes him to attack. In doing so, Rai is gravely wounded by Josuke's trap : in truth, Josuke had laid several bubbles in the room but some of them were hidden and spinning at high speed. By letting Wonder of U come to him, Josuke had hoped to let these trapped bubble kill the enemy Stand but instead, by sheer unluck, these bubbles wounded Mamezuku instead. Worse, one of those bubbles just pierced through Mamezuku's head.
Mamezuku collapses but declares that this fight is not over. Declaring that this "calamity" was instead "good fortune", Mamezuku decides to show a hidden aspect hidden within every Stand but of which nobody is aware of. Letting a bit of wire go down his finger, Mamezuku begins to spin the rope and explains to Josuke that his soap bubbles are actually soft, spinning lines. Opening his suit to reveal a gaping hole in his stomach, Mamezuku reveals the existence of the Spin to Josuke.
Joshu has brought the new Locacaca to Yasuho and declares that he'll save her. Despite Yasuho's misgivings, the Locacaca seems to be her only way to save herself. Yasuho explains to Joshu how the Equivalent Exchange works, but he loses himself in his own fantasies about the exchange and push himself onto a dismayed Yasuho. At the same time, Tooru decides to allow the exchange to happen in order to confirm the fruit's power. He makes several faint noises while hiding in the thicket, and this makes Yasuho realize that Tooru must be the enemy Stand User, as he's been near her since the beginning of the heroes' chase after Satoru Akefu. Yasuho performs an equivalent exchange with Joshu, and heals her arm. She then prepares to fight Tooru.
Thirteen minutes to the harvest of the Locacaca, it is revealed that Norisuke has been gravely wounded, being unconscious or worse. Somehow involved, Tsurugi drags Norisuke out of the office toward the balcony.
Characters & Stands
- According to a note by Araki in volume 2, the -lion in JoJolion's title is derived from the Ancient Greek εὐαγγέλιον (evangelion), in reference to the Gospels. "By combining this word with "JoJo", I've meant for the title to signify the existence of the protagonist "Josuke" in this world".
- It won the Grand Prize for manga at the 2013 Japan Media Arts Festival.
- At 9 years and counting of monthly publication, JoJolion's serialization is currently the longest of any JoJo part (a title that previously belonged to Steel Ball Run).