George Joestar III (ジョージ・ジョースターⅢ世, Jōji Jōsutā Sansei) is Johnny and Rina's first son and their second and last child, brother of his unnamed sister. He was born in 1898. When George's mother was on the verge of death, Johnny used the corpse to remove her disease, but the equivalent exchange only caused the illness to move onto George. The boy was saved when Johnny transferred the illness to himself with Tusk ACT 4, but the transfer also caused him to fall off his horse onto a bed of leaves with Les Feuilles, leading to a large rock being displaced onto his head shortly after. George was later found by agents from the United States and his mother, Rina.
As an adult, he is the father of two daughters and two sons, one of them being Joseph Joestar.
Norisuke Higashikata II (2代目 東方 憲助, Nidaime Higashikata Norisuke), born Johei Higashikata (東方 常平, Higashikata Jōhei) in 1872, is the third child and first son of Norisuke Higashikata I. He married Toyoko and fathered three daughters and two sons, one being Josho Higashikata.
Tomoko Higashikata (東方 伴子, Higashikata Tomoko) is the mother of Norisuke Higashikata IV (whose birth name was Josuke Higashikata). She reassures him when he asks questions about the family's curse. She sacrifices herself in winter 1963 when the Rock Disease was transferred from her son to her.
A Dorcus titanus palawanicus stag beetle owned by Josuke that Jobin offered as a gift. Later, Jobin challenges Josuke to a beetle battle, having Josuke's beetle fight with Jobin's own Dorcus titanus palawanicus. Josuke's beetle is victorious, and wins Jobin's Lamborghini. It is unknown what happened to Josuke's beetle afterwards.
Muneyuki (ムネユキ, Muneyuki) is a driver who shows disappointment after Karera Sakunami tells him to drive her and Josuke to Kira's apartment, because of the very short distance. Angered by his reaction, Karera throws a tantrum and the cab driver tries to kick her out of his cab, pointing out that there are cameras. She then settles down and coldly blames him for closing the door on her hair, saying she won't tell as long as he cooperates.
Atsunori Iwakiri (岩切 厚徳, Iwakiri Atsunori) is a star pitcher for the Seiten Birdies baseball team, nicknamed "God shoulder A-kun" by the crowd. In 2009 he had a salary of 300 million yen. However, in 2010 he damaged his shoulder with small hope of recovery and went on the disabled list just before he was going to be accepted into the major leagues. Desperate, he bought a Locacaca fruit for 200 million yen from Aisho Dainenjiyama to heal his shoulder. He made a full recovery in exchange for his teeth and lower jaw, which turned to stone.
Rena Nanami (菜々美 レナ, Nanami Rena) is a famous idol with many fans (especially male ones). Joshu is particularly infatuated with her and pressures his father to give him money to go to one of her conventions. After meeting her, he states it was an awesome experience and that her fingers are so smooth; however, her fingers and cuteness take a backseat to Yasuho's.
Miko (ミコ, Miko) was an unseen girl whom Yasuho knew when she was younger. It is implied that the two of them were friends. One day, Yasuho was supposed to come to Miko's birthday party, but completely forgot about it because she was distracted by her new hair clip. The moment she realized, she received multiple insulting texts from the many party attendants.
Mina (ミナ) is a classmate of Tsurugi Higashikata. She and her friends would taunt and harass Tsurugi because of the rumors of his grandmother burying a child's corpse. Mina teases Tsurugi by telling him to to ask Kaato how it was possible for her to bury the corpse without it rotting. Tsurugi glares at them and they mock his eyes. Mina then pushes Tsurugi further by flicking his forehead and saying it was his father who actually killed the boy. A frog then hops on Mina's foot and she falls into the nearby river.
After the incident, Mina's body is found collapsed in between the iron rails of the school gate. Her underwear was stained red from the injury. Although she was merely unconscious and wasn't dead, she wasn't responding. One of Mina's friends blames it on Tsurugi, saying she saw him make the gates move.
Later, the school principal says Mina's injuries were just minor light scratches and she's recovering fine in the hospital.
It is implied that the gates closing in on Mina was actually a calamity caused by the hospital director, as Mitsuba saw him standing near the gates moments after the incident on the school monitor.
For unknown reasons in Chapter 91, Mitsuba calls Mina "Miwa" (ミワ, Miwa).
Cindy (シンヂィ, Shindii), affectionally called "Cindy-chan", is a Flemish Giant rabbit that Yoshikage Kira met when he was 4. Her length was 127 centimeters, she weighed 12.5 kilograms, and she was 7 years old when she met Kira. She lived on a farm at the time. She and Kira had a photo together with him holding her. In the present, Holy Joestar-Kira mentions Cindy to Josuke Higashikata, asking him her length.
Satoru Akefu (明負 悟, Akefu Satoru) is the identity stolen by Toru's Stand, Wonder of U. A 79 year-old Japanese man living in the Ibaraki Prefecture, Akefu was a former member of the Society of Obstetrics and Gynecology, and a graduate of the TG University School of Medicine. Toru learns of Akefu's existence during his first encounter with Yasuho 10 years before the events of JoJolion, after asking her to look up elderly Japanese men who live in nursing homes, once had a license to practice medicine, and are cut off from their family. Yasuho states that while there aren't many individuals fitting that description, Akefu is the closest one to their location. Toru notes that Akefu's identity would be perfect to impersonate, and quickly leaves afterwards.