Vento Aureo - Chapter 6 
The zipper on Giorno's cheek starts to open, expanding down into his shoulder. Realizing he needs to retaliate, he starts thinking of the offensive capabilities of Gold Experience's life-giving ability, and how it might affect human beings. Gold Experience punches Bucciarati, giving him a surge of energy. However, this causes Bucciarati's brain to move faster than his body, making everything feel slower to him. Bucciarati then receives the most excruciating punch in his life: a punch to the jaw that he feels for what seems like minutes to him.