Dio is of the Vampirism (吸血鬼, Kyūketsuki) style. As such, a number of his abilities allow him to not only drain his opponents' health, but also to enter a Vampiric Power-Up Mode, boosting his movement speed and attack damage, among other things. All damage to him aside from Ripple-based will become "white damage", that can be healed over time, and inversely, Dio will take more damage from Ripple-based attacks.
Dio grabs the opponent and siphons their blood to restore his own health, an ability that can be easily incorporated into many of his combos. Successfully landing this attack will enter Dio into Vampiric Power-Up Mode. The skill will have no cooldown if Dio is already in Vampiric Power-Up Mode.
While Vampiric Power-Up Mode is active, Dio gains the ability to freeze opponents if he guards just before a non-projectile/DHA attack hits. This leaves them open to follow up attacks.
Dio fires off Space Ripper Stingy Eyes, sending opponents reeling if it hits. If Vampiric Power-Up Mode is active, the execution speed and distance of the attack is increased, and opponents hit are instead left crumpling and open to further attack.
Dio clasps his hands together then charges forward. If he connects with an opponent, he will lift them by the neck and drain their health, entering Vampiric Power-Up Mode if it is not already active. He will drain more health if the activating button is rapidly pressed. If Vampiric Power-Up Mode is active, the attack becomes unblockable and Dio will cover more distance.
Dio performs alternating knee kicks that knock opponents into the air before leaping, allowing him to continue his combo from the air. The brief pause that occurs upon his landing from the initial attack can be cancelled with a jump. If Vampiric Power-Up Mode is active, Dio receives super armor (unflinching to opponents' attack) during the attack, and will execute the follow-up leap quicker.
Dio performs a single, slow knee kick, freezing opponents hit and leaving them vulnerable to further attack. If Vampiric Power-Up Mode is active, the attack will execute quicker.
The skill gains the benefits of Vampiric Power-Up Mode whether or not it is actually active. It will also execute quicker, and Dio is granted complete invincibility during the attack.
The attack executes quicker and Dio's charging distance is increased further. He is also able to drain an even larger amount of health.
Dio is able to walk on certain walls and columns around the stage, granting him the ability to reach different areas of stages without needing to travel the conventional routes, or simply avoid attacks. Holding this activating button will allow him to climb higher, and he is able to attack from his vantage points.
When Dio's health hits zero for the first time, if his partner is still alive, he will momentarily rise and fire Space Ripper Stingy Eyes one more time at the closest opponent before being Retired, dealing considerable damage.
Dio freezes the opponent and attempts to unleash Space Ripper Stingy Eyes, quickly interrupted by DIO stopping time and pummeling them with The World into the air. DIO resumes time to allow Dio to fire off the attack, tilting his head to the side to avoid getting hit and watches as the beams obliterate the frozen opponent.