She is the daughter of Norisuke Higashikata I and wife of Johnny Joestar. Known as Rina Joestar (理那・ジョースター Rina Jōsutā) after marriage, she is the mother of George Joestar III and an unnamed daughter.
Rina is a young Japanese woman with a square face, typically seen in a yukata. She first had a traditional hairstyle, but is later shown with a ponytail.
Rina is described as a loving and caring wife. She is also seen as faithful during her peculiar ailment as she trusted Johnny to save her. While she was cured by the corpse parts, she showed great concern for her son George III, as it is revealed that he contracted the disease as well.
In the final chapter of Steel Ball Run, she meets Johnny Joestar on the ship crossing the Atlantic back to America with her father Norisuke. The two fell in love and eventually marry and live together on a ranch.
Years later, after the events of Steel Ball Run and before the events of JoJolion, Rina comes down with an incurable illness causing her to lose her memories and eventually turning her skin stiff and folded like origami. Johnny decides it is best to bring her to Japan to spend the last few days of her life in her hometown of Morioh.
He eventually travels back to New York to re-obtain the Saint's Corpse as a way of curing his wife's illness. After she is cured, the disease passes to their son George II. Johnny finally uses Tusk to take it upon himself, sacrificing himself for the sake for his family.
Afterwards, she is charged with Johnny's murder, but is released due to lack of evidence.